World News: 07:55 GMT Friday 10th August 2018. [Research and Markets via Globe Newswire via SPi World News]
Dublin, Aug. 10, 2018 (GLOBE NEWSWIRE) -- The report has been added to offering.
Hexosaminidase A deficiency (HEX A deficiency) results in a group of neurodegenerative disorders caused by the dysfunctional activity of the specific glycosphingolipid GM2 ganglioside. The disease occurs when cell membrane components known as gangliosides, accumulate to toxic levels, particularly in neurons in the brain and spinal cord, leading to the destruction of neurons and interference with biological functions. The predominant HEX A deficiency is Tay-Sachs disease (TSD) with its common acute infantile variant, which begins around six months of age and usually results in death by the age of four. Alternative variants of the pathology are the juvenile and the adult-onset TSD types.This report provides the current prevalent population for TSD disease across 19 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Poland, Netherlands, Czech Republic, Portugal, Russia, Turkey, Saudi Arabia, Japan, China, India, Australia, Brazil) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity. Providing a value-added level of insight from our analysis team, patients with main phenotypes and multiple symptoms of TSD have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.
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Related Topics: Central Nervous System Drugs
Globe Newswire: 07:55 GMT Friday 10th August 2018
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