World News: 21:01 GMT Wednesday 7th August 2019. [G1 Therapeutics via Globe Newswire via SPi World News]
RESEARCH TRIANGLE PARK, N.C., Aug. 07, 2019 (GLOBE NEWSWIRE) -- G1 Therapeutics, Inc. (Nasdaq: ), a clinical-stage oncology company, today provided a corporate and financial update for the second quarter ended June 30, 2019.
“Our most advanced investigational therapy, trilaciclib, has demonstrated significant benefits for people being treated with chemotherapy for small cell lung cancer and triple-negative breast cancer. We are pleased that the FDA has granted Breakthrough Therapy Designation based on myelopreservation data in small cell lung cancer, an important step toward making trilaciclib available to these patients. We look forward to working with the FDA during our pre-NDA meeting next month. We have also initiated parallel discussions with the FDA regarding promising data in metastatic triple-negative breast cancer, which showed improved overall survival,” said Mark Velleca, M.D., Ph.D., Chief Executive Officer. “In addition, we continue to make rapid progress across our pipeline, with emerging data suggesting that all three investigational therapies – trilaciclib, lerociclib and G1T48 – have the potential to improve outcomes for women with breast cancer and be used in early stages of their disease.”
Raj Malik, M.D., Chief Medical Officer and Senior Vice President, R&D, added, “We will present new data on trilaciclib, lerociclib and G1T48 at the upcoming ESMO congress. Of note, we will report the first clinical data from approximately 25 patients in a Phase 1 trial of G1T48, our oral selective estrogen receptor degrader. Based on data from this trial, we are planning to initiate a pivotal trial in 2020 with G1T48 for the treatment of ER+, HER2- breast cancer in combination with a CDK4/6 inhibitor.”
G1 is based in Research Triangle Park, N.C. For additional information, please visit and follow us on Twitter @G1Therapeutics.
Jeff MacdonaldHead of Investor and Public Relations919-213-9835
Globe Newswire: 21:01 GMT Wednesday 7th August 2019
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